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MIPAV Generatefusion
MIPAV is a framework not unlike Fiji, and the generatefusion plugin was developed in collaboration with the Shroff lab. It does intensity-based registration and joint deconvolution. You can download MIPAV at http://mipav.cit.nih.gov/ and then install the plugin.
In general this software is much slower and more computationally intensive that Fiji MVR but it has image-based registration that can handle registration of datasets without distinct interest points. (Image-based registration is in the future plans for MVR but it is not implemented as of August 2015).
MIPAV generatefusion is referenced in the 2014 Nature Protocols paper, though some things have changed since. Hopefully this will be a good home for updated information. add information